4-HYDROXY-NICOTINIC ACID METHYL ESTER
Methyl 4-hydroxynicotinate
CAS: 67367-24-2
Molecular Formula: C7H7NO3
4-HYDROXY-NICOTINIC ACID METHYL ESTER - Names and Identifiers
4-HYDROXY-NICOTINIC ACID METHYL ESTER - Physico-chemical Properties
| Molecular Formula | C7H7NO3 |
| Molar Mass | 153.14 |
| Density | 1.287±0.06 g/cm3(Predicted) |
| Boling Point | 338.3±22.0 °C(Predicted) |
| Flash Point | 118.8°C |
| Vapor Presure | 0.00593mmHg at 25°C |
| pKa | 8.18±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.517 |
4-HYDROXY-NICOTINIC ACID METHYL ESTER - Introduction
Methyl 4-hydroxynicotinate is an organic compound with the chemical formula C7H7NO3. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Methyl 4-hydroxynicotinate is a white to yellow crystalline solid.
-Solubility: It has low solubility in water, but can be dissolved in organic solvents such as ethanol and dimethylformamide.
Use:
-Pharmaceutical Field: Methyl 4-hydroxynicotinate is a nicotinic acid receptor agonist, which may be used to treat certain neurological diseases, such as Alzheimer's disease and Parkinson's disease.
-Chemical synthesis: It can be used as raw materials and intermediates in organic synthesis.
Preparation Method:
the preparation method of Methyl 4-hydroxynicotinate usually uses chemical synthesis route. The following is one of the common preparation methods:
1. First, the methyl ketone (Methyl ketone) and nitrous acid reaction, generate nitrosone (Nitroso ketone).
2. Next, nitrone reacts with hydrocyanic acid to generate cyanate ester (Cyanate ester).
3. Finally, the cyanate ester is hydrolyzed with alkali to generate Methyl 4-hydroxynicotinate.
Safety Information:
Methyl 4-hydroxynicotinate should follow routine laboratory safety practices. Although there is no clear toxicity data, it should be considered as a hazardous material and appropriate protective measures should be taken, such as wearing protective glasses and gloves, avoiding inhalation and skin contact. Before use, it is recommended to check the local chemical safety database for the latest safety information.
Nature:
-Appearance: Methyl 4-hydroxynicotinate is a white to yellow crystalline solid.
-Solubility: It has low solubility in water, but can be dissolved in organic solvents such as ethanol and dimethylformamide.
Use:
-Pharmaceutical Field: Methyl 4-hydroxynicotinate is a nicotinic acid receptor agonist, which may be used to treat certain neurological diseases, such as Alzheimer's disease and Parkinson's disease.
-Chemical synthesis: It can be used as raw materials and intermediates in organic synthesis.
Preparation Method:
the preparation method of Methyl 4-hydroxynicotinate usually uses chemical synthesis route. The following is one of the common preparation methods:
1. First, the methyl ketone (Methyl ketone) and nitrous acid reaction, generate nitrosone (Nitroso ketone).
2. Next, nitrone reacts with hydrocyanic acid to generate cyanate ester (Cyanate ester).
3. Finally, the cyanate ester is hydrolyzed with alkali to generate Methyl 4-hydroxynicotinate.
Safety Information:
Methyl 4-hydroxynicotinate should follow routine laboratory safety practices. Although there is no clear toxicity data, it should be considered as a hazardous material and appropriate protective measures should be taken, such as wearing protective glasses and gloves, avoiding inhalation and skin contact. Before use, it is recommended to check the local chemical safety database for the latest safety information.
Last Update：2024-04-09 21:01:54
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Product Name: Methyl 4-hydroxynicotinate Visit Supplier Webpage Request for quotation
CAS: 67367-24-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 67367-24-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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